Resource Hub

Poster

Toxicological Data Gap Filling of Ingredients; Comparison of Machine Learning Based Imputation and Traditional QSAR Methods

Whitehead, T. M.*, Strickland, J.*, Conduit, G. J.*, Borrel, A.**, Mucs, D., Baskerville-Abraham, I.
*Intellegens, **Inotiv

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Toxicological Data Gap Filling of Ingredients; Comparison of Machine Learning Based Imputation and Traditional QSAR Methods

Whitehead, T. M.*, Strickland, J.*, Conduit, G. J.*, Borrel, A.**, Mucs, D., Baskerville-Abraham, I.
*Intellegens, **Inotiv

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Comparison of Dimensionality Reduction Techniques for Chemical Space and Applicability Domain Determination of QSAR Model Training and Target Datasets

Urbina, F.*, Vignaux, P. A.*, Andersen, S.*, Mucs, D., Kanemaru, Y., Daikoku, A., Diaz-Fortier, N., Gafner, J., Hirata, T., Duarte, T., Neilson, L., Baskerville-Abraham, I., Ekins, S.*
*Collaborations Pharmaceuticals Inc.

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Comparison of Dimensionality Reduction Techniques for Chemical Space and Applicability Domain Determination of QSAR Model Training and Target Datasets

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Cheminformatics and data processing challenges in chemical grouping workflows for toxicological risk assessments

Hirn, C., Mucs, D., Buerger, A. N.*, Massarsky, A.*, Russel, A.*, Zoghby, N.*, Maier, A.*, Baskerville-Abraham, I.
*Stantec ChemRisk

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Cheminformatics and data processing challenges in chemical grouping workflows for toxicological risk assessments

Hirn, C., Mucs, D., Buerger, A. N.*, Massarsky, A.*, Russel, A.*, Zoghby, N.*, Maier, A.*, Baskerville-Abraham, I.
*Stantec ChemRisk

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Investigation on the biological effects of 3D reconstructed human airway tissue exposed at the air-liquid interface to aerosols generated from waterpipe tobacco blends with varying concentrations of cinnamaldehyde

Gafner, J., Lamboley, C., Vernaz, J.*, Constant, S.*, Neilson, L. *Epithelix

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Gafner, J., Lamboley, C., Vernaz, J.*, Constant, S.*, Neilson, L. *Epithelix

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Selecting an Inhalation Threshold of Toxicological Concern (TTC) through Chemical Space Visualization

Gafner, J., Kanemaru, Y., Mucs, D., Neilson, L., Baskerville-Abraham, I.

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Selecting an Inhalation Threshold of Toxicological Concern (TTC) through Chemical Space Visualization

Gafner, J., Kanemaru, Y., Mucs, D., Neilson, L., Baskerville-Abraham, I.

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Exploring Allergen Identification Methods: Integrating in silico Approaches with Mass Spectrometry and Genome Sequence Data

Diaz-Fortier, N., Mucs, D., Hirata, T., Daikoku, A., Baskerville-Abraham, I.

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Exploring Allergen Identification Methods: Integrating in silico Approaches with Mass Spectrometry and Genome Sequence Data

Diaz-Fortier, N., Mucs, D., Hirata, T., Daikoku, A., Baskerville-Abraham, I.

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Derivation of maximum acceptable group levels (MAGLs) for carvones in tobacco and nicotine products

Massarsky, A.*, Buerger, A.N.*, O’Neill, H.*, Gafner, J., Babcock, A., Neilson, L., Baskerville-Abraham, I., Maier, A.* *Stantec ChemRisk

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Derivation of maximum acceptable group levels (MAGLs) for carvones in tobacco and nicotine products

Massarsky, A.*, Buerger, A.N.*, O’Neill, H.*, Gafner, J., Babcock, A., Neilson, L., Baskerville-Abraham, I., Maier, A.* *Stantec ChemRisk

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Donor-to-donor variation of primary bronchial cells related to histology, tissue functions and responses to poly(I:C)

Ichikawa, S., Ishimori, K., Ito, S.

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Donor-to-donor variation of primary bronchial cells related to histology, tissue functions and responses to poly(I:C)

Ichikawa, S., Ishimori, K., Ito, S.

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Adverse outcome pathway-based in vitro assessment of mucus hypersecretion in three-dimensionally cultured bronchial epithelial cells

Matsumoto, R., Erami, K., Ichikawa, S., Sano, K., Muratani, S., Mori, A., Ito, S.

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Adverse outcome pathway-based in vitro assessment of mucus hypersecretion in three-dimensionally cultured bronchial epithelial cells

Matsumoto, R., Erami, K., Ichikawa, S., Sano, K., Muratani, S., Mori, A., Ito, S.

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Quantitative Adverse Outcome Pathway Analysis of Cigarette Smoke-induced Mucus Hypersecretion Using Bayesian Network Modeling

Ito, S., Erami, K., Ichikawa, S., Sano, K., Muratani, S., Mori, A., Matsumoto, R.

SOT 63rd Annual Meeting and ToxExpo, 2024

Poster

Method

Toxicological assessment

Quantitative Adverse Outcome Pathway Analysis of Cigarette Smoke-induced Mucus Hypersecretion Using Bayesian Network Modeling

Ito, S., Erami, K., Ichikawa, S., Sano, K., Muratani, S., Mori, A., Matsumoto, R.

Mar 2024

SOT 63rd Annual Meeting and ToxExpo, 2024

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